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WELCOME
Monday 3 February 2014 | 22:55 | |0 letters




GREETINGS!!BELOW ARE THE MODERN MEDICINE ANALGESIC-ASPIRIN-PARACETAMOL-CODEINE


Codeine
| 22:32 | |0 letters

CODEINE


Introduction : 
  • chemical formula C18H21NO3 
  • Molar mass 299.364 g/mol


Uses : 
  • To treat mild to moderate pain and to relieve cough

Side Effect :
  • Allergies - the swelling of skin and rashes

Paracetamol
| 21:10 | |0 letters

PARACETAMOL


Introduction :
  • chemically named N-acetyl-p-aminophenol
  • widely used over-the-counter analgesic (pain reliever) and antipyretic (fever reducer).
  • classified as a mild analgesic
  • Chemical formula C8H9NO2  
  • Molar mass  151.163 g/mol

Uses :
  • Paracetamol is approved for reducing fever in people of all ages. [The World Health Organization (WHO) recommends that paracetamol only be used to treat fever in children if their temperature is greater than 38.5 °C (101.3 °F)]
  •  It is better tolerated than aspirin in patients in whom excessive gastric acid secretion or prolongation of bleeding time may be a concern.
Side Effect :

  • Prolonged daily use increases the risk of upper gastrointestinal complications such as stomach bleeding, and may cause kidney or liver damage. 
  • Chronic users of paracetamol may have a higher risk of developing blood cancer.
  • Hearing Loss [Regular paracetamol use is correlated with increased hearing loss (ototoxicity)]



Aspirin
| 20:05 | |0 letters

Aspirin




Introduction
  • Also known as acetylsalicylic acid
  • Chemical formula : C9H8O4  
  • Molar mass : 180.157 g/mol

Uses :
  • Relieves pain caused by headache [ Among primary headaches, the International Classification of Headache Disorders distinguishes between tension headache (the most common),migraine, and cluster headache. Aspirin or other over-the-counter analgesics are widely recognized as effective for the treatment of tension headache. Aspirin, especially as a component of an acetaminophen/aspirin/caffeine formulation, e.g.Excedrin Migraine, is considered a first-line therapy in the treatment of migraine, and comparable to lower doses of sumatriptan. It is most effective at stopping migraines when they are first beginning. There is little data that suggest the aspirin is an effective treatment for cluster headache.]  
  • Reduces fever [pirin's ability to control fever is due to its action on the prostaglandin system through its irreversible inhibition of COX. ]  Prevent heart attacks and stroke [ In lower doses, aspirin has been known to prevent the progression of existing cardiovascular disease, and reduce the frequency of these events for those with a history of them. (This is known as secondary prevention.) 
  • Aspirin is a first-line treatment for the fever and joint pain symptoms of acute rheumatic fever. The therapy often lasts for one to two weeks, and is rarely indicated for longer periods. After fever and pain have subsided, the aspirin is no longer necessary, since it does not decrease the incidence of heart complications and residual rheumatic heart disease.
  • Blood clotting
                                       


Side Effect :
  • Causes internal bleeding ulceration (not suitable for gastric patients) 
  •  For a small number of people, taking aspirin can result in symptoms resembling an allergic reaction, including hives, swelling and headache. The reaction is caused by salicylate intolerance and is not a true allergy, but rather an inability to metabolize even small amounts of aspirin, resulting in an overdose.
  •  Aspirin can induce angioedema (swelling of skin tissues) in some people. In one study, angioedema appeared one to six hours after ingesting aspirin in some of the patients. However, when the aspirin was taken alone, it did not cause angioedema in these patients; the aspirin had been taken in combination with another NSAID-induced drug when angioedema appeared.

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